No. Most patients do not gain weight. Women have hormonally sensitive tissue in their hips and breasts. An increase in hormone may increase the size of these areas, mostly due to water weight. However, if a patient’s hormones are corrected and they train with weights, they will notice muscle growth and definition. Muscle growth increases the basal metabolic rate, which increases calorie burning efficiency. Most patients hit a wall where caloric needs exceed caloric intake. The body then turns to fat stores for energy. Fat seemingly melts off the body. Muscle per cubic centimeter weighs twice as much as fat. A given patient may notice their clothes getting looser, but their weight stays the same.